HYPERCHOLESTEROLEMIA

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چکیده

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Familial hypercholesterolemia: a case report

Abstract Familial hypercholesterolemia (FH) is a hereditary dislipidemia. Patients present with extremely high level of low-density lipoprotein cholesterol (LDL-C), which is due to mutation in the gene of LDL receptor. Homozygous patients (HoFH) whose incidence is 1 in 1.000.000 are at high risk of premature aortic valve stenosis, and coronary artery atherosclerosis. In homozygous individual...

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Familial hypercholesterolemia: A case report

Familial hypercholesterolemia (FH) is a hereditary dislipidemia. Patients present with extremely high level of low-density lipoprotein cholesterol (LDL-C), which is due to mutation in the gene of LDL receptor. Homozygous patients (HoFH) whose incidence is 1 in 1.000.000 are at high risk of premature aortic valve stenosis, and coronary artery atherosclerosis. In homozygous individuals cardiov...

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Pitavastatin in the Management of Hypercholesterolemia HYPERCHOLESTEROLEMIA

Pitavastatin((+)-monocalciumbis(3R,5S,6E)-7[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl3,5-dihydroxy-6-heptenoate]) (C50H46CaF2N2O8), is an entirely synthetic statin with a molecular weight of 880.98, that was initially developed by Nissan Chemical Industries Ltd., Tokyo, Japan, and later by Kowa Co. Ltd., Tokyo, (Figure 1).15 Pitavastatin exerts its potent pharmacological actions by strongly b...

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The Relationship between Nutrients Pattern and Hypercholesterolemia

Background: The prevalence of hypercholesterolemia is increasing globally. It is associated with a significant risk of developing type 2 diabetes mellitus and cardiovascular diseases. The aim of the current study was to explore the relationship of nutrients patterns and other lifestyle-related factors with the presence of hypercholesterolemia in a representative population of Iran. Methods: Die...

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Familial hypercholesterolemia.

Familial hypercholesterolemia (FH), caused by a defect in the low density lipoprotein (LDL) receptor, results in high plasma concentrations of LDL cholesterol due to both overproduction and delayed catabolism of LDL FH is also associated with significantly lower levels of plasma high density lipoprotein cholesterol and apolipoprotein (apo) A-I in both heterozygous and homozygous patients. Howev...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1923

ISSN: 0003-4932

DOI: 10.1097/00000658-192311000-00006